Singulair Hydrogen Peroxide, Micro Organisms, Immune Cells, Montelukast, Neurotoxin

I am posting the metabolism profile for montelukast. Maybe someone here has chemist friends who might know if it is possible that the dicarboxylic acid major metabolite could also have been derived from quinolinic acid under metabolic circumstances less than ideal. The quinoline ring, is a benzene-pyridine. Quinolinic acid, a dicarboxylic acid with a pyridine is produced by the oxidation of quinoline possibly by acid hydrogen peroxide. So the only structural difference between the dicarboxylic acid mentioned in the study as the major metabolite and quinolinic acid is nitrogen. Fascinating drug Singulair. Macrophages (immune cells) make quinolinic acid and release nitric oxide in order to kill micro-organisms. Quinolinic acid a neurotoxin.

Unless you are someone who plans to get help from experts, I would ignore this post. In my opinion, the only way that real answers will come from the investigation is that there is a provable chemical reason that the brain is affected by Singulair. I just post what I find and hope that eventually there will be experts who can explain why people are having such problems. I am unable to draw any conclusions from the report below.

dmd.aspetjournals.org/.../1/1996&journalcode=dmd