Tramadol (Ultram, Tramal (see below)) is a centrally-acting analgesic, used for treating moderate to moderately severe pain.

Tramadol is a synthetic stripped-down piperidine-analog of the phenantherane alkaloid Codeine and, as such, is an Opioid and also a pro-drug (Codeine is metabolized to Morphine, Tramadol is converted to M-1 aka O-desmethyltramadol). Opioids are chemical compounds which act upon one or more of the human opiate receptors (the euphoria, addictive nature and respiratory depression are mainly caused by the Mu(μ) 1 and 2 receptor. The opioid agonistic effect of Tramadol and its major metabolite(s) are almost exclusively mediated by the substance’s action at the μ-receptor. This characteristic distinguishes Tramadol from many other substances (including Morphine) of the opioid drug class, which generally do not possess Tramadol’s degree of subtype selectivity.

Source: http://en.wikipedia.org/wiki/Ultram

Ultram Discussions

  1. link Joker254k
    Ultram bad tooth
    I was put on tramadol 45mg and for bad tooth for the pain well I had to get rite off it because it was making me feel tired all the time and have ment - 58% more...
    Joker254k- over a year ago - in Ultram
  2. link Babyblue3
    Moraphine Allergy
    Can you take Ultram if you are allergic to morphine but you are not allergic to propoxyphene?
    Babyblue3- over a year ago - in Ultram
  3. link Wendim
    is ultram like percocet
    My doctor took me off percocet and put me on Ultram (tramadol hcl) 50mg. Is ultram like percocet? Will it have the same effect?
    Wendim- over a year ago - 1 Reply - in Ultram
  4. link Corider80
    sould i be worried
    grandmother accidentally took 5 50mg tabs of ultram this morning. 93 years old and about 90 lbs
    Corider80- over a year ago - in Ultram
  5. link Shamrock
    Ultram chronic back and neck pain, back and neck pain, twitch, vicodin, legs
    I was prescribed Ultram for chronic back and neck pain because I had been on Vicodin for a long time but did not want to be on a strong narcotic long- - 64% more...
    Shamrock- over a year ago - 1 Reply - in Ultram
  6. link Questorb
    Ultram arms and legs, motrin, six days, doctors, sleep
    Drove 500 miles from home...forgot to renew my ultram. Doctor would not renew without me coming in (have taken it for over two years). After 3 days co - 70% more...
    Questorb- over a year ago - in Ultram
  7. link Susan225
    Ultram meloxicam, arthritis
    This is effective for arthritis. Works better than anything else with Meloxicam.
    Susan225- over a year ago - in Ultram
  8. link Nancylouise
    Ultram blood pressure medications, extreme fatigue, antidepressants, headaches
    Ultram was prescribed for me for "chronic every day headaches". It has been effective. I have been on antidepressants and I am usually unabl - 75% more...
    Nancylouise- over a year ago - in Ultram
  9. link Mgvititoe1
    Compared to Vicodin
    How does Ultram compare to Vicodin? Is it equally as effective? Is Vicodin stronger or the same? Side effects comparison? Which one is more effective?
    Mgvititoe1- over a year ago - in Ultram
  10. link Avonrep
    Ultram ultram er, wheeler accident, 4 wheeler, norco, drs
    I was in a 4 wheeler accident and fractured my shoulder, I'm having problems with drs, but my prim. care Phys. put me on ULTRAM ER 100MG if I take 1 d - 55% more...
    Avonrep- over a year ago - in Ultram
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